ANDROSTENEDIONE
ANDROSTENEDIONE

by: Dr. Gregory J. Porter MD Internal Medicine, AZ

Androstenedione is scientifically proven to increase lean muscle mass, energy levels, endurance, sexual drive, and a sense of well being. This scientific breakthrough gives consumers an alternative to medically reproduced testosterone. Androstenedione allows your body to naturally increase it's own testosterone production levels.

Technical Data:

Androstenedione, structurally known as 4-androsterone-3,17 is produced from both 17a-hydroxyprogesterone and dehydroepiandrosterone (DHEA) in the adrenals, ovaries and testes. Androstenedione is a metabolite of (DHEA) that serves as a direct precursor in the biosynthesis of testosterone. Androstenedione converts directly into testosterone, while DHEA and pregnenolone requires 3 to 4 bio-reactions before they are converted into testosterone.

Androstenedione is a molecular chain identical to testosterone, except that it is missing a hydrogen atom at the 17th position. As the androstenedione molecule is processed by the liver, a hydrogen atom is added to the 17th position by the enzyme 17b-hydroxysteroid dehydrogenase which forms the testosterone molecule therefore increasing serum testosterone levels for about an hour.

What are the effects of an increased testosterone level? ...

Increased energy levels, minimal recovery time from exercise (bodybuilding), increased libido (sex drive) and an overall sense of well being.

How much and for how long will androstendione increase my testosterone level? ...

Many factors affect the conversion of androstenene to testosterone. Expect two to three times the normal level after taking 100mg.- 30 minutes to three hours after ingestion. One study concluded that 50mg. Androstendione raised plasma testosterone levels from 140% to 183% of normal and 100mg. raised testosterone levels 300% plus.

What is the recommended level for men? ...

Testosterone levels vary greatly in men, so suggested doses are impossible to estimate. Significant results have been achieved with 100 to 300mg. 30 to 60 minutes before exercise.

Will this effect my natural testosterone production and what are the side effects? ...

When taking any product naturally produced in the human body it is normally suggested that one use that product (steroid) in a cycling manner. Example- 4 weeks on 1 week off, 5 days on weekends off-etc. to prevent (steroid) receptor down-regulation. Cycling androstene (testosterone) will keep the body producing as much androstene (testosterone) as possible without resulting in natural hormone secretion down regulation. Possible side effects are highly unlikely due to the short time span that each dose of Androstendione elevates testosterone levels.

How long has androstene been in use and what are the results? ...

During the undisputed reign of the East German Olympic Team of the 1970's Androstendione was used profusely. A nasal spray was used as one route of administration for these athletes. Results were not well documented, however, Androstendione was obviously a contributing factor to their success.

What is the current legal status of Androstendione? ...

In the United States the legal status of Androstendione is the same as dehydroepiandrosterone (DHEA). It is not classified as a anabolic steroid or a controlled substance by either the FDA or the DEA and is legal for sale over the counter thanks to recent food supplement legislation, ie: the Dietary Supplement Health and Education Act of 1994 which states that any substance may qualify as a dietary supplement as long as it was not previously marketed as a drug in this country and as long as the substance meets the definition: Natural substances found in the human body or plant life or substances used to supplement the diet to increase the total dietary intake.

WARNING:

Consult with your physician prior to use if you have any medical conditions. Women should not use if pregnant or lactating.

  • Testosterone levels after administration of 100 mg. of Androstendione to women athletes: 220 ng. per dl. blood at 30 minutes 660 ng. per dl. blood at 60 minutes 380 ng. per dl. blood at 90 minutes

*NOTE: The normal testosterone level for a female is under 100 ng. per dl. blood which means that a females testosterone levels more than doubles at 30 minutes; is more than 6 fold at 60 minutes and is still nearly 4 times the normal level at 90 minutes after ingestion. A males testosterone level normally ranges from 300 ng. per dl. blood to 1000 ng. per dl. blood. Testosterone levels for a male after ingestion of 100 mg. of Androstendione are around 100 ng. per dl. blood less than the numbers listed in each time frame plus the normal natural level. Based on these numbers, a male who normally has 500 ng. testosterone per dl. blood would be around 620 ng. at 30 minutes, 1060 ng. at 60 minutes and 780 ng. per dl. blood at 90 minutes after ingestion.

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