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widespread than was once believed, the most common causes
of hair loss in women are not related to inherited genes,
but to temporary metabolic problems associated with pregnancy,
unusual stress, chemotherapy, crash diets/anorexia, thyroid
hormone deficiency, major surgery, severe infection or high
fever. Certain drugs can also take their toll on once healthy
tresses. However, these conditions are usually temporary
and once the "trauma" is alleviated, the hair shedding stops
and healthy regrowth occurs with time.
"Female
pattern" hair loss is another matter. Unlike men, women
rarely become "bald" in the true sense, but many experience
significant overall thinning and a reduction in hair shaft
diameter, particularly around the forehead and crown of
the scalp as they age. Most often, this pattern begins to
develop at age 40 or with the onset of menopause. In fact,
before menopause only about 13% of women experience hair
thinning. After menopause, those reporting the problem increases
to 37%.
Females
experience "female pattern" hair loss because estrogen levels
decline in the skin with age. Before menopause, various
forms of estrogen block or "oppose" the steroid hormone
responsible for hair loss, testosterone, resulting in low
levels of DHT (dihydrotestosterone) being produced in the
skin and follicle region. Once females enter menopause,
their levels of estrogen decline and more testosterone is
then bio-available to be converted to DHT (the known cause
of non-traumatic hair loss) in the root bulb and stem cell
regions. This results in a shorter hair growth cycle, finer
hair and eventually, general effluvium or shedding. AS women
enter their 80's and 90's, the follicle itself can shrink
and stop producing hair completely.
183TM
Topical solution is designed to counteract this increase
in DHT production in the follicle caused by the loss of
estrogen. 183TM TS
works by preventing the metabolism of DHT in the scalp through
temporarily lowering the pH in the follicle region. This
shuts down the enzymes used by testosterone to produce DHT.
At a lower pH, the activity of these enzymes (5 alpha reductase
types 1 and 2) is stopped for five or six hours. If 183TM
TS is applied at least three times a day, we believe that
DHT levels are lowered sufficiently to allow the root bulb
and stem cells to return to pre-menopausal productivity
rates. This results in the observed cessation of shedding
and thicker, healthier hair throughout the forehead and
crown regions within two to four months.
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